Pfizer BioNTech Vaccine

Science • Medicine
A third Pfizer dose is likely needed within 12 months, says CEO
A third Pfizer dose is likely needed within 12 months, says CEO
Credit: U.S. Secretary of Defense, via Wikimedia Commons (Creative Commons Attribution 2.0)

Albert Bourla, CEO of Pfizer, stated that a third dose of the BioNTech-Pfizer vaccine is "likely" needed within 12 months in order to get fully vaccinated.

“A likely scenario is that there will be likely a need for a third dose, somewhere between six and 12 months and then from there, there will be an annual revaccination, but all of that needs to be confirmed. And again, the variants will play a key role,” so Bourla.

Science • Medicine
BioNTech-Pfizer vaccine to offer protection against Covid-19 for at least 6 months
BioNTech-Pfizer vaccine to offer protection against Covid-19 for at least 6 months
Credit: Logo via Pfizer & BioNTech

According to a published research by Pfizer, the BionTech-Pfizer Covid-19 vaccine offers protection against Covid-19 for at least 6 months.

"Pfizer Inc. and BioNTech SE today announced updated topline results from analysis of 927 confirmed symptomatic cases of COVID-19 observed in their pivotal Phase 3 study through March 13, 2021, showing the Pfizer-BioNTech COVID-19 vaccine, BNT162b2, was 91.3% effective against COVID-19, measured seven days through up to six months after the second dose," so the statement.

Albert Bourla, Chairman and Chief Executive Officer of Pfizer said that the data confirmed "the favorable efficacy and safety profile of our vaccine", adding that the "high vaccine efficacy observed through up to six months following a second dose and against the variant prevalent in South Africa provides further confidence in our vaccine’s overall effectiveness."

Science • Medicine
BioNTech-Pfizer and Moderna vaccines 90% effective at preventing infections study shows
BioNTech-Pfizer and Moderna vaccines 90% effective at preventing infections study shows
Credit: unsplash.com/Marisol Benitez

A study from the US Centers for Disease Control and Prevention (CDC) has shown that both BioNTech-Pfizer and Moderna vaccines are 90% effective at preventing infections, including asymptomatic infections, with the first dose showing 80% efficacy.

“Reducing the risk for transmissible infection, which can occur among persons with asymptomatic infection or among persons several days before symptoms onset, is especially important among health care personnel, first responders, and other essential and frontline workers given their potential to transmit the virus through frequent close contact with patients and the public,” the report concluded.

Science • Medicine
BioNTech-Pfizer to start pediatric Covid-19 vaccine trial
BioNTech-Pfizer to start pediatric Covid-19 vaccine trial
Credit: Illustration: Pendect, Ashley Winkler (Creative Commons Attribution ShareAlike 4.0)

BioNTech and Pfizer announced Thursday that they are launching pediatric trials of their Covid-19 vaccine on children 12 years and under.

"Together with our partner BioNTech, we have announced a global study to further evaluate our #COVID19 vaccine in healthy children ages 6 months to 11 years. We are proud to start this much needed study for children and families eagerly awaiting a possible vaccine option," Albert Bourla,

Chairman and CEO of Pfizer, announced on Twitter. "As a father and a scientist, I would like to thank our participants and their parents and caregivers for enrolling in the study. We need to continue gathering evidence on the safety and efficacy of #COVID19 vaccines for important populations, including children."

Regional News • Americas • South America
A helicopter from Uruguayan Air Force transporting Pfizer vaccines crashed. No casualties, all doses destroyed

Pfizer vaccines arrived in Uruguay on Wednesday. Today, an Air Force helicopter was responsible for transporting 180 doses crashed. The authorities started an investigation suspecting that the cause was a mechanical failure.

The crew managed to operate an emergency landing, resulting in no casualties but several injuries. After landing the vehicle was on fire and the load was completely lost.

Regional News • Americas • Brazil
Brazilian government signs contract with Pfizer to buy 100 million doses of Covid-19 vaccine
Brazilian government signs contract with Pfizer to buy 100 million doses of Covid-19 vaccine
Credit: Illustration: Pendect, Ashley Winkler.

The Brazilian government signed a contract with Pfizer for the purchase of 100 million doses of vaccine against Covid-19.

According to the schedule released by the Ministry of Health, the jabs are to be delivered between April and September.

Regional News • Americas • South America
The first batch of Pfizer/Biontech vaccines arrived in Uruguay
The first batch of Pfizer/Biontech vaccines arrived in Uruguay
Credit: Ashles Winkler for Pendect

On Wednesday the first batch of 50.000 Pfizer/Biontech vaccines arrived in Uruguay. The jabs will be applied first to health workers.

50.000 more doses are expected to arrive in the next week, plus 60.000/week later until complete the order of 460.000.

Regional News • Oceania
New Zealand bought enough Pfizer/BioNTech vaccine for entire population
New Zealand bought enough Pfizer/BioNTech vaccine for entire population
Credit: U.S. Secretary of Defense, via Wikimedia Commons (Creative Commons Attribution 2.0)

Prime Minister Jacinda Ardern reported that New Zealand has purchased enough of Pfizer/BioNTech's Covid-19 vaccine to inoculate its entire population. The government has signed an advanced purchases agreement with the vaccine manufacturer for an additional 8.5 million doses. Pfizer/BioNTech's Covid-19 vaccine will be the country's primary vaccine.

Whilst the Pfizer vaccine does need to be kept at ultra-cold temperatures, this challenge is offset by only having to deal with one vaccine, rather than multiple vaccines with multiple protocols. It will simplify our vaccine roll out," Arden said.

Regional News • Americas • Brazil
Brazilian Government decides to buy Pfizer and Janssen Covid-19 vaccines
Meeting between the Brazilian Ministry of Health and Janssen
Meeting between the Brazilian Ministry of Health and Janssen Credit: Ministério da Saúde

The Brazilian Ministry of Health decided on Wednesday to sign contracts for the purchase of vaccines against Covid-19 from Pfizer and Janssen laboratories. The contracts are being drafted and must be signed by the beginning of next week, with a determination of the quantity of doses to be delivered.

The country is experiencing the most serious moment of the pandemic, with reports of collapse in the health system in different states and successive records of deaths by Covid-19, which has increased criticism of the folder for the delay in negotiations to obtain vaccines against the disease.

Business • Health Care
BioNtech-Pfizer vaccine stops 89.4 percent of virus transmission
BioNtech-Pfizer vaccine stops 89.4 percent of virus transmission
Credit: Ashles Winkler for Pendect, Logos Pifzer & BioNTech

According to an initial study, the vaccine from BioNtech and its US partner Pfizer apparently largely prevents the transmission of the coronavirus. This is the result of a large observational study conducted jointly with the Israeli Ministry of Health. The study found that the vaccine was 89.4 percent effective in preventing Sars-CoV-2 infections.

The study is based on data from 1.1775 million vaccinated Israelis. Vaccinated people are thus not only protected from disease but also appear to have a high probability of no longer infecting other people.

According to the data, the vaccine also has an efficancy of nearly 96 percent after two doses of vaccination. According to the Israeli Ministry of Health, two weeks after the second dose of vaccine, 95.8 percent fewer infections were found in vaccinated people than in unvaccinated people. One week after the second dose, efficacy is 91.9 percent, according to the report.

Regional News • World
BioNTech/Pfizer vaccine can be stored in higher temperatures than initially thought, new data shows
BioNTech/Pfizer vaccine can be stored in higher temperatures than initially thought, new data shows
Credit: U.S. Secretary of Defense, via Wikimedia Commons (Creative Commons Attribution 2.0)

The BioNTech/Pfizer Covid-19 vaccine had originally been approved for storage at a minimum of -60 degrees celsius but according to new data, the vaccine is more robust than initially thought and can be stored at minus 25 to minus 15 degrees celsius.

Higher temperature storage would result in "greater flexibility" and "even easier to transport and use", so BioNTech’s chief executive Ugur Sahin.

Regional News • Europe • European Union
BioNTech and Pfizer pledge 75m additional doses to EU
BioNTech and Pfizer pledge 75m additional doses to EU
Credit: Pfizer, BioNTech

On Monday, BioNTech and Pfizer said they would increase their Covid-19 vaccine delivery the European Union in the second quarter of 2021, pledging an additional 75 million doses. Both BioNTech-Pfizer and AstraZeneca have recently experienced production delays, resulting in slower vaccine distribution schedules in the EU.

Regional News • Europe • European Union
EU Commission orders up to 300 million more vaccine doses from BioNtech
EU Commission orders up to 300 million more vaccine doses from BioNtech
Credit: Ashles Winkler for Pendect

The EU Commission has concluded a contract for up to 300 million more doses of the Corona vaccine from the Mainz-based company BioNtech and its US partner Pfizer. 75 million doses of this should be available as early as the second quarter of 2021, EU Commission chief Ursula von der Leyen said in Brussels on Friday.

Back in November, the EU Commission ordered up to 300 million doses of vaccine from BioNtech/Pfizer for all 27 states - a firm order for 200 million doses and an option for 100 million more, which was recently pulled.

In Germany, BioNtech is currently working on a new production site in Marburg. If this goes into operation in February as planned, the company will be able to massively expand vaccine production.

Health
European Medicines Agency approves drawing six instead of five vaccination doses per BioNtech ampoule in EU
European Medicines Agency approves drawing six instead of five vaccination doses per BioNtech ampoule in EU
Credit: Ashley Winkler for Pendect

From now on, more people can be vaccinated with the Covid-19 vaccine from one ampoule of the manufacturers BioNtech and Pfizer.

The European Medicines Agency (EMA) has approved that six instead of five doses may be drawn from an ampoule, said a spokesman for the Federal Ministry of Health in Berlin on Friday.

This approval of six instead of five vaccinations per ampoule applies only to the EU. In the remaining countries outside the EU, the national authorities decide whether to change the vaccine approval.

Regional News • Europe • European Union
BioNTech founders warn of Covid-19 vaccine supply issues in EU
BioNTech founders warn of Covid-19 vaccine supply issues in EU
Credit: Ashley Winkler for Pendect

BioNTech is working flat out with partner Pfizer to boost production of their Covid-19 vaccine, its founders said, warning there would be gaps in supply until other vaccines were rolled out. The German biotech start-up has led the vaccine race but its shot has been slow to arrive in the EU due to relatively slow approval from the bloc’s health regulator and the small size of the order placed by Brussels.

The delays have caused consternation in Germany, where some regions had to temporarily close vaccination centres days after the launch of an inoculation drive on December 27th.

Regional News • Middle East
Israel: 1 million people vaccinated against coronavirus
The President of Israel, Reuven Rivlin, visits the vaccination center of the Maccabi Healthcare Services in Jerusalem. Wednesday, December 30, 2020. Photo credit: Haim Tzach / GPO.
The President of Israel, Reuven Rivlin, visits the vaccination center of the Maccabi Healthcare Services in Jerusalem. Wednesday, December 30, 2020. Photo credit: Haim Tzach / GPO. Credit: Haim Zach / Government Press Office (Israel), Wikimedia Commons (Creative Commons Attribution ShareAlike 3.0)

Over a million people in Israel have been vaccinated against the coronavirus, the highest amount for a country globally. This results in 11.55 in 100 people being vaccinated, compared to 1.47 in 100 people in the UK. Israel started vaccinations on December 19th with a rate of 150,000 vaccinations per day.

Business • Health Care
Biontech applies for change in approval to get more doses from vials
Biontech applies for change in approval to get more doses from vials
Credit: Illustration by Ashley Winkler for Pendect (Creative Commons Attribution ShareAlike 4.0)

One ampoule of Biontech vaccine can often be used to produce six rations instead of five. The Mainz-based manufacturer Biontech has now submitted an application to the European Medicines Agency Ema for a change in the conditions of approval. The Ema had told the German newspaper SPIEGEL on Tuesday that if Biontech submitted an application to change the terms of its marketing authorisation, it would be "rapidly" reviewed by its human medicines committee.

Biontech is lobbying for doctors to be allowed to draw six full vaccine doses of 0.3 ml each from the provided vials containing a total of 2.25 ml of finished vaccine in the future - provided they can draw up six full doses.

Health
One day delay in Pfizer vaccine delivery to Spain due to logistical issue
One day delay in Pfizer vaccine delivery to Spain due to logistical issue
Credit: Illustration: Pendect, Ashley Winkler. (Creative Commons Attribution ShareAlike 4.0)

Spanish Health Minister Salvador Illa announced that Pfizer has postponed the delivery of a new batch of the coronavirus vaccine to the country by one day to Tuesday due to a logistics hurdle.

The cool boxes designed by Pfizer have GPS trackers so the company can deal with potential storage issues en route. The vaccine must be stored at ultra-low temperatures of about -70 degrees Celsius before being shipped to distribution centres in specially designed cool boxes filled with dry ice.

"Due to a minor logistical issue, we have rescheduled a limited number of our deliveries," Andrew Widger, Pfizer's director for media relations said.

Regional News • Americas • South America
Mexico, Chile and Costa Rica begin Covid-19 mass vaccination
Mexico, Chile and Costa Rica begin Covid-19 mass vaccination
Credit: Illustration by Ashley Winkler for Pendect

Mexico became the first country in Latin America to start vaccinating for Covid-19. The first person to receive one of the initial shipment of 3000 doses of the Pfizer-BioNTech vaccine was intensive-care nurse María Irene Ramirez.

Shortly after Mexico started vaccinating, Chile and Costa Rico followed suit.

Regional News • Europe • France
France: Pfizer-BioNTech Covid-19 vaccine approved by medical regulator
France: Pfizer-BioNTech Covid-19 vaccine approved by medical regulator
Credit: unsplash.com/CDC

The French medical regulator has approved the vaccine developed by Pfizer and BioNTech on Thursday.

"The vaccine can be used for people aged 16 and over, including elderly", said the Haute Autorité de la Santé (HAS).